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. 2011 Jun 28;16(7):5460–5495. doi: 10.3390/molecules16075460

Table 7.

ATH of acetophenone performed in ionic liquids.

Entry Ligand Solution S/C [a]; Time; Temp.;
Conversion (%)		 % ee (config.) [b] Ref. [c]
1 (R,R)-23 [d] HCOOH/Et3N/[C4C1C1Im]PF6 [e] 200; 24 h; 35 °C; > 99 > 99 [132]
2 (S,S)-24 [f] HCOOH/Et3N/[bmim][PF6] [g] 100; 24 h; r.t.; 98 92 (S) [72]
3 (R,R)-5a [h] HCOOH/Et3N/[bmim][PF6] [g] 100; 8 h; 40 °C; 100 97 (R) [99]

[a] Molar ratio substrate/catalyst; [b] See corresponding references for details on determination of ee and product configuration; [c] Reference containing data for a given entry; [d] The catalyst was formed in situ from (R,R)-TsDPEN and the corresponding ligand; [e] 1-butyl-2,3-dimethylimidazolium hexafluoro-phosphate; [f] The catalyst was formed in situ from the [RuCl2(η6-benzene)]2 dimer and (S,S)-24; [g] [bmim][PF6] = 1-butyl-3-methylimidazolium hexafluorophosphate; [h] The catalyst was formed in situ from the [RuCl2(η6-p-cymene)]2 dimer and (R,R)-5a.