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. 2012 Oct 9;17(10):11849–11863. doi: 10.3390/molecules171011849

Table 1.

Time distribution of selectivity in betulin oxidation without Al2(SO4)3 at molar ratio ν Cr6+/ νbetulin equal to 3 in acetone at room temperature.

Time, min Conversion of betulin (1), % Products in reaction mixture, % (HPLC, IR and NMR-spectra control)
Betulinic aldehyde (4) Betulonic aldehyde (3) Betulonic acid (2) Other unknown products
2 5 15–20 55 20–25
5 7 15 50–60 20–25
10 12 5 60 10 25
20 17 60 10 30
65 25 50 20 30
80 30 40 30 30
160 37 35 35 30
300 40 20 50 30
400 50 70 30
150 * 100 0–5 95–100

*: The experiment with Al2(SO4)3.