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Effect of YNS-PY-F on SDF-1α induced CXCR4 internalization. (A) Negative control: EGFP-CXCR4 mainly distributed in the cytoplasm of 293 T cells treated by SDF-1α; (B) AMD3100 at 10 μM: EGFP-CXCR4 still mainly distributed in the cell membrane of cells treated by SDF-1α and AMD3100; (C) YNS-PY-F at 200 μg/mL: EGFP-CXCR4 mainly distributed in the cytoplasm of 293 T cells treated by SDF-1α andYNS-PY-F. The scale bar was 25 μm.
