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. 2012 Sep 13;17(9):11067–11078. doi: 10.3390/molecules170911067

Table 1.

Particle size (x10, x90 [nm]) of APIs IIII and concentration [%] of Tween 80 in dichloromethane (DCM) or acetone (AC). All the presented results are reported as medium value of four independent measurements, repeatability was up to 6%. Samples that contained nanoparticles <200 nm are bolded; nanoparticles <10 nm are indicated by grey background. (S.No. = sample number).

API/Solvent Tween 80
S.No. 1% S.No. 3% S.No. 5% S.No. 10%
x10 x90 x10 x90 x10 x90 x10 x90 Particle size [nm]
I/DCM 1 1 1 2 139 200 3 222 289 4 158 231
I/AC 5 2038 2242 6 9963 10,276 7 9344 10,281 8 7 8
II/DCM 9 218 288 10 3149 3464 11 97 189 12 18 19
II/AC 13 14 21 14 57 81 15 9345 10,281 16 2 3
III/DCM 17 63 94 18 91 99 19 3640 4005 20 62 79
III/AC 21 332 366 22 2 3 23 53 77 24 12 19