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Antitumor activity of synthesized guanidines.
| Compound | Average number of tumors per disc | % Inhibition of tumors |
|---|---|---|
| 1 | 2.0 | 73 |
| 2 | 1.5 | 80 |
| 3 | 2.0 | 73 |
| 4 | 3.0 | 60 |
| 5 | 2.0 | 73 |
| 6 | 1.5 | 80 |
| 7 | 2.0 | 73 |
| 8 | 3.0 | 60 |
| 9 | 2.0 | 73 |
| 10 | 2.0 | 73 |
| 11 | 3.0 | 60 |
| 12 | 1.5 | 73 |
| AT10 | 7.5 | --- |
| Blank | 00 | 100 |
a Potato disc antitumor assay, concentration: 500 µg/mL in DMSO; b More than 20% tumor inhibition is significant; c Data represents mean value of 12 replicates.
