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Exclusion of the central or systemic antinociceptive effect of FKB. FKB (500 µg/paw, i.pl.) was administered to the right hind paw 2 h and 45 min following carrageenan administration into both hind paws and nociceptive threshold was measured in the right (ipsilateral; IL) or left (contralateral; CL) hind paw. Each column represents the mean ± S.E.M. (n = 6). *** p < 0.001 when compared with control (C) group (One-way ANOVA followed by Dunnett’s post hoc test).
