Table 4.
Minimum inhibition concentration (MIC) (mg/mL), minimum bactericidal concentration (MBC) (mg/mL) and selectivity index (SI) of C-5-bromo-2-hydroxophenylcalix[4]-2-methylresorcinarene (I).
| Microorganism | MIC mg/mL | MBC mg/mL | SI |
|---|---|---|---|
| MRSA (Gram-positive) | 1.563 | 25 | 0.256 |
| Sa (Gram-positive) | 6.25 | 12.5 | 0.064 |
| Ef (Gram-positive) | 6.25 | 12.5 | 0.064 |
| Ea (Gram-negative) | >25 | - | - |
| Pa (Gram-negative) | >25 | - | - |
Note: MRSA = methicillin-resistant Staphylococcus aureus); Sa = Staphylococcus aureus); Ef = Enterococcus faecalis; Ea = Enterobacter aerogenes; Pa = Pseudomonas aeruginosa (-ve); SI = selectivity index = CC50/MIC (refer to Section 2.4.3).