. 2014 Jul 17;19(7):10455–10472. doi: 10.3390/molecules190710455

Table 3.

Binding specificity and cellular processing of NOTA-PEG_n-RM26, (n = 2, 3, 4 and 6).

	PEG₂	PEG₃	PEG₄	PEG₆
In vitro binding specificity test, % blocked uptake of ⁶⁸Ga-labeled variants on PC-3 (BT474) cells in presence of excess of non-labeled tracer	94.5 ± 0.1	98.0 ± 0.1 (95.3 ± 0.2)	98.2 ± 0.1	95.5 ± 0.3
In vitro binding specificity test, % blocked uptake of ¹¹¹In-labeled variants on PC-3 (BT474) cells in the presence of excess of non-labeled tracer	97.7 ± 0.2	94.0 ± 0.2 (95.0 ± 0.4)	95.0 ± 0.9	94.8 ± 0.4
Internalization rate by PC-3 (BT474) cells, % internalized radioactivity from total cell associated at 24 h continuous incubation	33 ± 3	31 ± 2 (32 ± 2)	30 ± 1	35 ± 2