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. 2014 Jul 30;19(8):11196–11210. doi: 10.3390/molecules190811196

Figure 2.

Figure 2

Effect of Rhy on the PI3K/Akt signaling and the downstream apoptosis-related proteins. (A) The expression of p-Akt, Akt, mTOR, p-mTOR, p-BAD, BAD, and cleaved caspase 3 in Sham (S), pMCAO (M), Rhy-L (RL), Rhy-H (RH), Rhy-H + wortmannin (RW) and pMCAO + wortmannin (MW) groups; (B) Densitometry analysis; (C) Immunohistochemical staining of p-BAD and cleaved caspase 3 at 24 h after pMCAO; (D) Bar graph shows quantitative data from each group (* p < 0.05 Rhy and Sham vs. pMCAO, # p < 0.05 RW vs. RH).