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. 2014 May 28;19(6):7008–7039. doi: 10.3390/molecules19067008

Table 4.

10 hits obtained in the second screening round.

ID Structure Inhibition at 10 µM (%) IC50 (µM) T2D T3D Fusion Score T2D/T3D First Round Hit_ID First Round Hits Chemo Type
3 graphic file with name molecules-19-07008-i022.jpg 83 0.053 0.9 0.88 1.78 1.02 2 graphic file with name molecules-19-07008-i009.jpg A2
5 graphic file with name molecules-19-07008-i023.jpg 94 0.105 0.86 0.87 1.73 0.99 2 graphic file with name molecules-19-07008-i009.jpg A2
4 graphic file with name molecules-19-07008-i024.jpg 90 0.779 0.92 0.83 1.75 1.1 2 graphic file with name molecules-19-07008-i009.jpg A2
6 graphic file with name molecules-19-07008-i025.jpg 88 1.1 0.89 0.82 1.71 1.09 2 graphic file with name molecules-19-07008-i009.jpg A2
8 graphic file with name molecules-19-07008-i026.jpg 86 1.4 0.81 0.69 1.50 1.18 2 graphic file with name molecules-19-07008-i009.jpg A2
7 graphic file with name molecules-19-07008-i027.jpg 89 3.0 0.84 0.78 1.62 1.08 2 graphic file with name molecules-19-07008-i009.jpg A2
1 graphic file with name molecules-19-07008-i028.jpg 51 1.7 0.85 0.69 1.54 1.24 1 graphic file with name molecules-19-07008-i017.jpg B1
2 graphic file with name molecules-19-07008-i029.jpg 61 1.4 0.84 0.67 1.51 1.25 1 graphic file with name molecules-19-07008-i017.jpg B1
9 graphic file with name molecules-19-07008-i030.jpg 62 3.2 0.85 0.65 1.5 1.31 1 graphic file with name molecules-19-07008-i017.jpg B1
10 graphic file with name molecules-19-07008-i031.jpg 62 2.4 0.88 0.64 1.52 1.38 7 graphic file with name molecules-19-07008-i020.jpg A11