ETA enhanced inhibitory effect of Taxol on growth of HeLa tumors. HeLa tumor-bearing nude mice were given 10 mg/kg (Taxol-H) or 5 mg/kg (Taxol-L) of Taxol every other day for 5 doses, or 200 mg/kg/day of ETA (ETA-H) for 9 doses, or the combination of Taxol-H and 50 mg/kg/day of ETA (Taxol-H + ETA-L), or the combination of Taxol-L and ETA-H (Taxol-L + ETA-H). Body weight (A) and tumor weight (B) were recorded and expressed as mean value ± standard error of mean (n = 6). Compared to Vehicle group, data were significantly different at ** p < 0.01. Compared to Taxol-H group, data were significantly different at ▲
p < 0.05.