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. 2014 May 22;19(5):6707–6726. doi: 10.3390/molecules19056707

Figure 5.

Figure 5

Effects of oligomers on motor function. Forty-five or six-week-old SAMP8 mice were administered vehicle (Veh, water p.o., n = 4), while another two groups were administered oligomers orally at doses of 10 mg/kg body weight/day (O (10), n = 4) using a stomach tube until death. For the remaining group of mice, the mean food intake was restricted to 60% until death (FR, n = 4). SAMR1 mice (Cont, 45-46 weeks old, n = 4) were used as a control group. One hundred and thirty-nine days after the start of administration, the time spent on the inclined surface without dropping was measured (A). The number of rotations measured for 30 min (B). Administration was continued during the tests. a p = 0.0159 (A: Student’s t-test).