Scheme 3.
Equatorial location of the hydroxy group in lactone 7a as the stereochemical consequence of microbial hydrolytic dehalogenation (similar to a SN2 mechanism) of chloro-3a, bromo-4a and iodolactone 5a proceeding with inversion at C-2.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.