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. 2015 Feb 3;20(2):2636–2657. doi: 10.3390/molecules20022636

Figure 2.

Figure 2

Pre-treatment with gedunin impairs zymosan-induced (A) ET-1 expression at 2 h and production of (B) IL-6, (C) TNF-α, (D) LTB4, (E) PGE2 and (F) the number of lipid bodies in synovial leukocytes 6 h after stimulation. Results are expressed as mean ± SEM. * p ≤ 0.05 vs. saline group, + p ≤ 0.05 vs. zymosan group.