Table 4.
Percentage inhibition of compounds 6, 4a, and 5a against three test fungi.
| Compd. | R1 | R2 | Inhibition Rate (%) at 100 μg/mL | ||
|---|---|---|---|---|---|
| F. graminearaum | B. cinerea | R. solani | |||
| 6a | 3-Cl | Me | 14.9 ± 2.8 | 27.1 ± 1.0 | 15.4 ± 3.6 |
| 6b | 3-Cl | Et | 27.4 ± 1.0 | 42.0 ± 3.5 | 35.0 ± 7.8 |
| 6c | 3-Cl | n-Pr | 47.4 ± 0.9 | 72.0 ± 1.1 | 73.2 ± 1.3 |
| 6d | 3-Cl | i-Pr | 45.1 ± 1.9 | 72.5 ± 1.9 | 78.7 ± 1.6 |
| 6e | 3-Cl | n-Bu | 46.5 ± 0.9 | 68.1 ± 1.1 | 67.7 ± 0.9 |
| 6f | 3-Cl | i-Bu | 48.8 ± 2.4 | 73.9 ± 1.1 | 74.8 ± 1.3 |
| 6g | 3-Cl | Bn | 31.6 ± 3.5 | 65.7 ± 1.0 | 60.2 ± 2.5 |
| 6h | H | i-Bu | 51.8 ± 1.8 | 82.2 ± 3.0 | 66.7 ± 1.3 |
| 6i | 4-F | i-Bu | 53.7 ± 2.3 | 79.2 ± 1.6 | 70.6 ± 1.6 |
| 6j | 2-Cl | i-Bu | 48.6 ± 1.0 | 51.3 ± 2.5 | 60.7 ± 2.2 |
| 6k | 4-Cl | i-Bu | 39.4 ± 3.5 | 75.0 ± 1.6 | 71.4 ± 2.9 |
| 6l | 4-Br | i-Bu | 54.1 ± 3.0 | 70.3 ± 2.2 | 75.8 ± 3.0 |
| 6m | 2-Me | i-Bu | 52.8 ± 2.1 | 66.5 ± 3.8 | 69.4 ± 0.8 |
| 6n | 3-Me | i-Bu | 55.0 ± 2.4 | 77.1 ± 1.0 | 71.4 ± 2.2 |
| 6o | 4-Me | i-Bu | 46.3 ± 3.6 | 71.6 ± 2.1 | 73.4 ± 3.5 |
| 6p | 3-OMe | i-Bu | 60.6 ± 7.1 | 61.9 ± 1.0 | 69.8 ± 6.7 |
| 6q | 3-CF3 | i-Bu | 40.4 ± 1.1 | 56.4 ± 2.1 | 63.5 ± 3.4 |
| 4a | H | — | 1.8 ± 1.4 | 16.2 ± 2.3 | 0 |
| 5a | H | — | 2.5 ± 1.8 | 14.3 ± 1.2 | 2.5 ± 1.0 |
| Drazoxolon | — | — | 75.1 ± 2.3 | 95.0 ± 1.5 | 94.9 ± 1.1 |