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. 2016 Aug 12;21(8):1052. doi: 10.3390/molecules21081052

Figure 1.

Figure 1

IC50 curves of β-cryptoxanthin for human UGTs activities including UGT1A1 for β-estradiol-3-glucuronidation (A); UGT1A3 for chenodeoxycholic acid 24-acyl-β-d-glucuronidation (B); UGT1A4 for trifluoperazine-N-glucuronidation (C); UGT1A6 for serotonin-O-glucuronidation (D); UGT1A9 for propofol-O-glucuronidation (E); and UGT2B7 for zidovudine-5′-glucuronidation (F) in human liver microsomes, and UGT2B15 for 4-methylumbelliferyl glucuronidation (G) in recombinant human UGT2B15 supersomes. Data are the mean ± standard deviation of triplicate determinations. The dashed lines represent the best fit to the data using non-linear regression.