Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Transition from G2-checkpoint arrest to mitosis. For simplicity, a solid line represents how CDK1–cyclin B triggers entry into mitosis and a dashed line represents Cdk1-inactivating pathways (CHK1/WEE1/Cdc25C/Cdk1, MYT1/Cdk1, and PP2A/WEE1/Cdc25C). Abbreviations: Cdk1, cyclin-dependent kinase 1; CHK1, checkpoint kinase 1; MYT1, membrane associated tyrosine/threonine 1 kinases; PP2A, protein phosphatase 2.
