Table 4.
Discrepancies in the results between ITC studies in cultured prostate cancer cell lines and animal models.
| ITC | Factor | In Vitro | In Vivo |
|---|---|---|---|
| PEITC | Bak | ↑ [149] | ↓ [150] |
| PEITC | Bcl-XL | ↓ [84,149] | ↑ [150] |
| PEITC | Vimentin | ↑ [151] | ↓ [151] |
| SFN | Bcl-XL | ≈ [99] | ↓ [147] |
| SFN | Bid | ≈ [99] | ↑ [152] |
Abbreviations: ↑, enhanced expression; ≈, no change in expression; ↓, reduced expression; Bak, Bcl-2 homologous antagonist/killer; Bcl-XL, B-cell lymphoma-extra large; Bid, BH3 interacting-domain death agonist; PEITC, phenethyl isothiocyanate; SFN, sulforaphane.