. 2016 Jun 18;21(6):794. doi: 10.3390/molecules21060794

Table 3.

Experimental condition optimization for the intramolecular metal-catalyzed cyclization of 12.

Entry	CuI (mol %)	Ligand ^a	Cs₂CO₃ (Equiv)	Conversion ^b (%) (Isolated Yield)
1	10	20	2	100
2	10	-	2	100 (80)
3	5	-	2	80 ^b
4	10	-	-	65 ^b
5	-	-	2	- ^c

^a 1,10-phenanthroline; ^b Reaction conversion was determined by ¹H NMR analysis; ^c Traces.