Simplified view of inflammasomes pathway. AIM: Absent In Melanoma receptors, ASC: apoptosis-associated speck-like protein, DAMPs: Danger-Associated Molecular Patterns, HO-1: Heme-Oxygenase 1, IL1-β: Interleukin 1 béta IL-18: Interleukin 18, NF-κB: Nuclear Factor-kappa B, NLRs: Nucleotide-binding domain and Leucin-rich repeat Receptors, NOS: Nitric Oxyde Species, Nrf2: Nuclear factor erythroid 2–Related Factor 2, PAMPs: Pathogen-Associated Molecular Patterns, PRRs: Pattern Recognition Receptors, R.E.: Responsive Elements, RLHs: Retinoic acid-inducible gene Like Helicase Receptors, ROS: Reactive Oxygen Species, TXNIP: Thioredoxin Interacting Protein, TXR; thioredoxin.