Table 1.
Lipid profile parameter and biochemical markers of bone formation and resorption.
| Parameters | Sham | OVX | LRV | HRV | ALEN |
|---|---|---|---|---|---|
| Lipid profile | |||||
| Serum AST (U/L) | 127.5 ± 25.97 | 136.7 ± 26.09 | 134.6 ± 22.81 | 129.6 ± 27.97 | 112.5 ± 23.53 |
| Serum ALT (U/L) | 26.4 ± 5.24 | 29.1 ± 4.53 | 26.9 ± 8.68 | 25.9 ± 5.01 | 26.4 ± 4.63 |
| Bone formation | |||||
| Serum ALP (U/L) | 34.0 ± 6.80 | 45.7 ± 7.85 * | 44.9 ± 5.22 * | 42.6 ± 4.24 * | 45.1 ± 7.66 * |
| Serum OC (ng/mL) | 17.9 ± 3.77 | 21.6 ± 7.65 | 20.8 ± 6.47 | 20.0 ± 3.86 | 17.7 ± 5.46 |
| Bone resorption | |||||
| Urinary DPD (nM BCE/mM Cr) | 90.9 ± 47.04 | 70.2 ± 52.14 | 78.9 ± 53.90 | 92.8 ± 30.18 | 43.1 ± 13.35 |
| Urinary NTx (nM BCE/mM Cr) | 5.9 ± 2.19 | 5.9 ± 1.36 | 6.3 ± 1.06 | 7.5 ± 2.04 | 7.2 ± 2.57 |
Sham, sham-operated control; OVX, ovariectomized rats without treatment; LRV, ovariectomized rats treated with low-dose RC vinegar; HRV, ovariectomized rats treated with high-dose RC vinegar; ALEN, ovariectomized rats treated with alendronate. * There were statistical differences among the experimental groups by one-way ANOVA and Duncan’s multiple range tests (p < 0.05). Data are expressed as the mean ± SD (n = 8). AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; OC, osteocalcin; DPD, deoxypyridinoline; BCE, bone collagen equivalent; Cr, creatinine.