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Photomicrographs of the kidneys following cadmium and CNFE treatments. Kidney tissues from (a) control and (b) CNFE-treated groups showing essentially normal tubules. In the Cd-treated group (c–e), severe tubular necrosis (asterisk), apoptosis (arrowhead), and vacuolar degeneration (arrow) were observed. Treatment with CNFE either at 1 g/kg (f) or 2 g/kg (g) markedly ameliorated all renal damages caused by cadmium. Hematoxylin and eosin (H & E), 40×.
