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. 2016 Nov 22;21(11):1598. doi: 10.3390/molecules21111598

Scheme 1.

Scheme 1

The synthetic route for the preparation of the thiosemicarbazone derivatives 110. Reagents and conditions: (i) NH2NH2·H2O, ethanol, rt, 4 h; (ii) Ar-CHO, ethanol, reflux, 8 h.