Figure 3.

Schematic representation of the mechanism of encapsulation and release of microparticles by the bilayer self-folding microtubes. The microtubes are formed from a film of poly(N-isopropylacrylamide-co-4-acryloylbenzophenone) (poly(NIPAM-ABP) and polycaprolactone (PCL) mixed with magnetic nanoparticles. The microparticle (a) adsorbs into the bilayer film; at low temperature (less than LCST); the film (b) folds forming a microtube that encapsulates the microparticle; and upon high temperature (above LCST) (c) it unfolds releasing the microparticle. (Reproduced from Zakharchenko et al. [62] with permission of The Royal Society of Chemistry.)