Table 3.
Residues detected on mtGS PPI as a potential HS (buried area ≥ 40 Å2 in at least 10 monomers) with the respective mean value of ΔΔGbind determined by cASM, standard error of mean (SEM) and their classification as HS (red), WS (orange) or NS (yellow).
| Resid | ΔΔGbind | SEM | Classif |
|---|---|---|---|
| Y20 | 0.41 | 0.20 | NS |
| I31 | 1.15 | 0.32 | NS |
| H34 | 4.12 | 0.31 | HS |
| F35 | 1.88 | 0.13 | NS |
| I64 | 4.48 | 0.40 | HS |
| H65 | 1.20 | 0.30 | NS |
| D68 | −0.12 | 0.52 | NS |
| R84 | 7.06 | 0.74 | HS |
| F99 | 1.53 | 0.43 | NS |
| V142 | 2.92 | 0.26 | WS |
| F144 | 2.60 | 0.21 | WS |
| N149 | 3.48 | 0.13 | WS |
| S151 | −0.09 | 0.07 | NS |
| Y153 | 7.18 | 0.17 | HS |
| E154 | −0.33 | 0.27 | NS |
| R176 | 6.96 | 1.20 | HS |
| Y178 | 3.42 | 0.22 | WS |
| R181 | 9.57 | 1.12 | HS |
| Y186 | 3.79 | 0.26 | WS |
| F187 | 3.84 | 0.29 | WS |
| V189 | 3.71 | 0.21 | WS |
| V196 | 0.85 | 0.24 | NS |
| D200 | −1.28 | 0.44 | NS |
| K250 | 14.54 | 0.28 | HS |
| W254 | 4.46 | 0.28 | HS |
| M263 | 6.94 | 0.17 | HS |
| F268 | 3.60 | 0.13 | WS |
| K328 | 13.60 | 0.17 | HS |
| R345 | 16.09 | 0.36 | HS |
| R347 | 12.97 | 0.49 | HS |
| I355 | 3.17 | 0.15 | WS |
| V463 | 4.40 | 0.24 | HS |
| I465 | 0.87 | 0.17 | NS |
| R466 | 8.82 | 0.14 | HS |
| H468 | 4.50 | 0.08 | HS |
| Y470 | 3.89 | 0.06 | WS |
| E471 | 9.67 | 0.29 | HS |
| F472 | 5.54 | 0.09 | HS |
| L474 | 2.06 | 0.14 | WS |
| Y475 | 5.49 | 0.10 | HS |
| Y476 | 5.74 | 0.29 | HS |
| D477 | −2.78 | 0.28 | NS |