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. 2016 Apr 1;21(4):443. doi: 10.3390/molecules21040443

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© 2016 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Silymarin treatment reduced restraint-induced apoptotic cascade. (A) Immunoblot analysis of caspase8, Bid, Bax, caspase3, PARP, and GAPDH. (B) Quantitative analysis of blots. Each value is the mean ± SD for four mice. Values with different letters (a, b) are significantly different from one another (one-way ANOVA followed by Newman-Keuls multiple range test, p < 0.05). CON; control mice, Sily; only silymarin-treated mice, RS; restraint stressed mice, RS + Sily; restraint-stressed mice with silymarin treatment.