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. 2016 Jul 8;21(7):886. doi: 10.3390/molecules21070886

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© 2016 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of 6-gingerol (GNL) on the cell cycle distribution of HepG2 cells. The cells were exposed to GNL (B); DOX (C); or combination of GNL and DOX (D) for 24 h and compared to control cells (A); Cell cycle distribution was determined using DNA cytometry analysis and different cell phases were plotted (E) as percentage of total events; Sub-G cell population was taken as representative of late apoptosis/necrosis and was plotted as percent of total events (F). Data is presented as mean ± SD; n = 3. *: significantly different from control group.