Table 1.

Samples before and after knocking out the target component and knock-out constituents in safflower series of herb pairs on PAF-induced platelet aggregation (mean ± SD, n = 4).

Group	Aggregation Ratio (%)	Aggregation Inhibition Ratio (%)	Contribution Degree (%)
Negative control	85.83 ± 4.70	—	—
Positive control	45.65 ± 1.78 **	46.81 ± 5.33	—
HSYA	72.40 ± 7.18 *	15.64 ± 8.37	—
ASYB	54.35 ± 12.31 **	36.67 ± 14.34	—
CF	33.08 ± 3.43 **	61.46 ± 4.00	—
CF-A	46.48 ± 6.66 **△	45.85 ± 7.76	25.40
CF-B	40.55 ± 3.52 **△	52.75 ± 4.10	14.17
CF-PS	51.00 ± 4.07 **	40.58 ± 4.74	—
CF-PS-A	59.45 ± 5.53 **△	30.73 ± 6.44	24.26
CF-PS-B	53.47 ± 3.35 **	37.70 ± 3.91	—
CF-GL	46.83 ± 3.68 **	45.44 ± 4.28	—
CF-GL-A	54.30 ± 5.28 **	36.73 ± 6.15	—
CF-GL-B	56.25 ± 7.50 **	34.46 ± 8.74	—
CF-GR	18.28 ± 4.04 **	78.71 ± 4.71	—
CF-GR-A	53.18 ± 10.34 **△△	38.04 ± 12.05	51.67
CF-GR-B	27.25 ± 5.57 **△	68.25 ± 6.49	13.29
CF-AS	11.95 ± 5.57 **	86.08 ± 2.58	—
CF-AS-A	31.08 ± 2.65 **△△	63.79 ± 3.06	25.89
CF-AS-B	18.73 ± 4.82 **△	78.18 ± 5.62	9.17
CF-SL	36.45 ± 4.42 **	57.53 ± 5.16	—
CF-SL-A	48.78 ± 5.72 **△	43.17 ± 6.66	24.96
CF-SL-B	47.53 ± 6.17 **△	44.63 ± 7.19	22.43
CF-SM	25.60 ± 6.53 **	70.17 ± 7.61	—
CF-SM-A	28.45 ± 6.27 **	66.85 ± 7.31	—
CF-SM-B	27.03 ± 4.35 **	68.51 ± 5.07	—
CF-AR	28.98 ± 5.71 **	66.24 ± 6.65	—
CF-AR-A	38.53 ± 3.70 **△	55.11 ± 4.31	16.80
CF-AR-B	32.65 ± 6.06 **	61.96 ± 7.06	—

* p < 0.05, ** p < 0.01 vs. control group. ^Δ p < 0.05, ^ΔΔ p < 0.01 vs. the respective original solutions. Positive control was ginkgolide B at the concentration of 0.5 mg·kg⁻¹ for PAF induced platelet aggregation assay. The sample concentration was 0.8 g crude drugs/g and the monomer components (HSYA, ASYB) were basically the same as in the original solutions.