Table 2.

Samples before and after knocking out the target component and knock-out constituents in safflower series of herb pairs on AA-induced platelet aggregation (mean ± SD, n = 4).

Group	Aggregation Ratio (%)	Aggregation Inhibition Ratio (%)	Contribution Degree (%)
Negative control	78.38 ± 8.66	—	—
Positive control	58.23 ± 5.45 **	25.71 ± 3.44	—
HSYA	71.25 ± 2.12	9.09 ± 2.71	—
ASYB	73.15 ± 2.44	6.67 ± 3.11	—
CF	11.15 ± 2.14 **	85.77 ± 2.73	—
CF-A	12.78 ± 2.86 **△	83.70 ± 3.65	4.89
CF-B	20.25 ± 2.23 **△△	74.16 ± 2.85	9.43
CF-PS	11.04 ± 3.25 **	55.02 ± 14.09	—
CF-PS-A	63.07 ± 7.75 *△△	19.53 ± 2.70	64.50
CF-PS-B	70.75 ± 2.43 △△	9.73 ± 3.10	82.32
CF-GL	14.78 ± 7.52 **	81.15 ± 9.60	—
CF-GL-A	32.45 ± 5.55 **△△	58.60 ± 7.08	27.79
CF-GL-B	59.60 ± 2.61 **△△	23.96 ± 3.33	70.48
CF-GR	42.22 ± 2.72 **	30.24 ± 4.50	—
CF-GR-A	53.18 ± 6.10 △	12.14 ± 10.08	59.84
CF-GR-B	56.28 ± 3.20 △△	7.02 ± 5.28	76.78
CF-AS	37.82 ± 2.85 **	37.50 ± 4.71	—
CF-AS-A	59.22 ± 5.00 △△	2.15 ± 8.26	94.27
CF-AS-B	59.82 ± 6.66 △△	1.16 ± 11.00	96.92
CF-SL	51.67 ± 0.91 **	34.08 ± 1.16	—
CF-SL-A	62.87 ± 2.48 *△△	19.79 ± 3.17	41.93
CF-SL-B	54.77 ± 2.50 **	30.12 ± 3.19	—
CF-SM	28.30 ± 3.35 **	63.89 ± 4.28	—
CF-SM-A	26.83 ± 3.61 **	65.77 ± 4.61	—
CF-SM-B	33.93 ± 4.14 **	56.71 ± 5.29	—
CF-AR	27.40 ± 7.36 **	65.04 ± 9.39	—
CF-AR-A	40.83 ± 4.40 **△	47.90 ± 5.62	26.35
CF-AR-B	39.22 ± 3.55 **△	50.41 ± 4.49	28.75

* p < 0.05, ** p < 0.01 vs. control group. ^Δ p < 0.05, ^ΔΔ p < 0.01 vs. the respective original solutions. Positive control was ginkgolide B at the concentration of 0.5 mg·kg⁻¹ for AA induced platelet aggregation assay. The sample concentration was 0.8 g crude drugs/g and the monomer components (HSYA, ASYB) were basically the same as in the original solutions.