Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 29;8(19):5469–5481. doi: 10.7150/thno.28295

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Ivyspring International Publisher

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

The role of B6ME-NPs in vitro. (A) αS-overexpression in SH-SY5Y cells as a PD cell model was detected via CLSM. Nuclei: DAPI, blue; control cells: mCherry, red; αS-SH: mCherry-SNAC, red. Scale bar: 20 μm. (B) The TEM images showing the differences of of vesicles and cell membrane curvature induced by B6M-NPs or B6MA-NPs in SH-SY5Y cells (48 h). Red triangles mark curvature, blue triangles mark vesicles. Scale bar: 2 μm. (C) Quantitation of (A). (D) Quantitation of vesicular NPs in (B). (E) Expressions of lipid raft-related proteins (EGFR, Contactin1, flotillin1, flotillin2 and neurotrimin) detected by Western Blot. (F-J) Quantitation of each protein in (E). Error bars represent mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001; (Tg + PBS), (Tg + B6ME-NPs) vs. WT. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001; (Tg + EGCG) vs. (Tg + B6ME-NPs).