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. 2018 Nov 8;23(11):2914. doi: 10.3390/molecules23112914

Table 1.

The most potent spirolactone-type diterpenoid derivatives of each series.

Compound IC50 [µM]
K562 MGC-803 CaEs-17 Bel-7402 MCF-7
51 1.27 2.24 1.05 1.54 / a
68 0.39 1.28 0.60 1.39 / a
76d 1.74 1.16 3.75 0.86 / a
82 0.69 2.20 / a 1.80 0.68

a “/” represents not tested.