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. 2018 Oct 27;23(11):2787. doi: 10.3390/molecules23112787

Table 6.

Polyphenol-loaded carbon-based nanohybrids for the treatment of cancer.

No. Components of Nanoparticles Method of Preparation Polyphenol + Synergistic Agent Type of Cancer In Vitro Model/In Vivo Model Promisingly Treated with the Fabricated Nanotherapeutic Formulation References
1 Graphene oxide Reduction method Tea polyphenols Colon cancer HT29, SW48 [133]
2 Graphene oxide Reduction method Resveratrol Ovarian cancer A2780 [134]
3 Polycapro-lactone–MWNT Electrospinning Tea polyphenols Lung cancer A549 [136]
4 Polycapro-lactone–MWNT Electrospinning Tea polyphenols Hepatic HepG2 [136]
5 Gelatin–MWNT Coating Catechin + Radiotherapy Prostate cancer DY-145, PC-3, LNCap [138]
6 Gelatin–MWNT Coating Catechin Cervical cancer HeLa [139]
7 Polymeth-acrylic acid–MWNT Radical coupling Quercetin Cervical cancer HeLa [137]
8 Polymeth-acrylic acid–MWNT Radical coupling Quercetin + Cisplatin Neuroblastoma IMR-32 [140]

Note: MWNT—Multiple-walled carbon nanotubes.