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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Biomaterials. 2018 Oct 15;188:130–143. doi: 10.1016/j.biomaterials.2018.10.015

Fig. 5. The tumorigenesis of osteosarcoma cells and osteogenesis of osteoblasts cultured within the scaffolds in vivo.

Fig. 5.

(A-D) Representative images of nude mice and harvested samples constructed with (A, B) MG63 cells and (C, D) hFOB1.19 cells in 9 hydrogels. Red dotted circles indicate the tumor and the neoplasms. Scale bar: 1 cm. (E-F) HE staining of the (E) MG63 tumors and (F) hFOB1.19 neoplasms. Scale bar: 50 µm. (G) CD133 immunohistochemistry of the MG63 tumors. Scale bar: 50 µm. (H) OCN immunohistochemistry of the hFOB1.19 neoplasms. Scale bar: 50 µm.