Fig. 1.
PHT effects on calcium homeostasis in hippocampal cells. (a) PHT decreased intracellular free Ca2+ according to concentration. The data were expressed as mean ± SD of three independent experiments. Asteric (*) symbol indicates significant changes (p < 0.05) than [Ca2+]i in the presence of NAD+ (b) Cyclase activity of CD38 suppressed by different concentrations of PHT. Enzymatic activity decreased to half of maximum in the presence of 8.1 μM inhibitor. The data were expressed as mean ± SD of three independent experiments