Table 2.
Induction of thymic lymphoma in mice with low-LET ionising radiation
| Malignancy | Mouse strain | Age | Sex | Dosage | Fractionation | Latency | spontaneous frequency | Induced frequency | Ref. |
|---|---|---|---|---|---|---|---|---|---|
| Thymic Lymphoma | C57BL (C57BL/6, C57BL/6J) | 4–6 weeks | Male, Female | ~1.7 Gy | 4× once weekly | 3–6 months | <1% | > 90% | (159) |
| Thymic Lymphoma | BALB/c (BALB/ cHeA) | 4 weeks | Male, Female | ~1.7 Gy | 4× once weekly | 2.5– 9.5 months | 5–6% females; 0% males |
77% (Females) 86% (Males) |
(148,153) |
| Thymic Lymphoma | NFS | 4 weeks | Male, Female | ~1.7 Gy | 4× once weekly | 3–6 months | >1% within 12 months | 90% (females) 89% (males) |
(176,177) |