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Kaplan-Meyer curves depicting overall survival of patients with de novo AML according to the presence or absence of NF1 mutations. (a) Patients <60 years of age belonging to the ELN 2017 adverse risk group with any NF1 mutation (red) compared with patients without NF1 mutations (blue). (b) Patients <60 years of age with NF1 Thr676 mutations (red) compared with patients without these mutations (blue).
