(A) S100B and race both significantly correlated with Verbal Memory, Visual Motor Speed, and Reaction Time. (B) Evidence of mediation: S100B and race significantly correlated. Controlling for race, the associations between S100B and Verbal Memory, Visual Motor Speed, and Reaction Time all became nonsignificant. Race remained significantly correlated with all composite scores while controlling for S100B effects. Numerical values represent regression weights (r or β). *p < 0.01, **p < 0.001. S100B = S100 calcium binding protein B.