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. 2018 Sep 28;59(11):2049–2060. doi: 10.1111/epi.14567

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© 2018 The Authors. Epilepsia published by Wiley Periodicals, Inc. on behalf of International League Against Epilepsy.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Permeability of [³H]sucrose and [¹⁴C]phenytoin evaluated in EPI‐EC GR inhibition (MF), EPI‐EC no inhibition, and HBMEC DIV‐BBB. A‐A2, [³H]sucrose permeability was comparable across experimental conditions. B‐B2, [¹⁴C]phenytoin permeability was higher (1.20 × 10⁻⁷ cm/s) in EPI‐EC GR‐inhibited DIV‐BBB (P ≤ 0.05) compared with EPI‐EC untreated BBB (4.90 × 10⁻⁸ cm/s)