Table 3.
Adjusted mean change (95% CI) in CVD risk and risk factors between enrollment and the second home visit among women postmenopausal at enrollment a
| N | 10-year CVD risk | Weight (kg) | BMI (kg/m2) | Waist (cm) | Systolic BP (mmHg) | |
|---|---|---|---|---|---|---|
| All | ||||||
| BC | 517 | 4.0 (3.5, 4.5) | −0.8 (−1.4, −0.2) | −0.0 (−0.3, 0.2) | 3.1 (2.3, 3.9) | 4.5 (3.4, 5.7) |
| No BC | 655 | 4.5 (4.0, 4.9) | −0.6 (−1.1, −0.0) | 0.1 (−0.1, 0.3) | 3.4 (2.7, 4.1) | 4.9 (3.9, 6.0) |
| P-value | 0.161 | 0.600 | 0.431 | 0.547 | 0.590 | |
| BMI<25 at enrollment | ||||||
| BC | 183 | 2.9 (2.4, 3.4) | 0.7 (−0.0, 1.4) | 0.5 (0.2, 0.8) | 4.5 (3.4, 5.6) | 4.1 (2.3, 5.9) |
| No BC | 249 | 3.4 (3.0, 3.8) | 0.6 (−0.1, 1.2) | 0.4 (0.2, 0.7) | 3.7 (2.8, 4.7) | 5.2 (3.7, 6.7) |
| P-value | 0.128 | 0.781 | 0.635 | 0.295 | 0.377 | |
| BMI 25.0–29.9 at enrollment | ||||||
| BC | 183 | 4.1 (3.3, 4.8) | 0.1 (−0.9, 1.2) | 0.4 (0.0, 0.8) | 3.1 (1.9, 4.4) | 5.5 (3.6, 7.5) |
| No BC | 227 | 4.6 (4.0, 5.3) | 0.5 (−0.4, 1.4) | 0.5 (0.1, 0.8) | 4.3 (3.2, 5.5) | 6.2 (4.4, 7.9) |
| P-value | 0.266 | 0.574 | 0.801 | 0.176 | 0.642 | |
| BMI 30+ at enrollment | ||||||
| BC | 151 | 5.2 (3.9, 6.4) | −4.2 (−5.7, −2.6) | −1.3 (−1.9, −0.8) | 1.4 (−0.3, 3.0) | 3.4 (1.2, 5.7) |
| No BC | 179 | 5.9 (4.7, 7.0) | −3.1 (−4.6, −1.7) | −0.6 (−1.1, −0.1) | 1.8 (0.3, 3.3) | 3.4 (1.4, 5.5) |
| P-value | 0.416 | 0.351 | 0.073 | 0.729 | 0.997 | |
| Chemotherapy, no endocrine therapy | ||||||
| BC | 44 | 3.2 (1.5, 4.9) | −0.4 (−2.6, 1.8) | 0.0 (−0.8, 0.8) | 4.9 (2.3, 7.6) | 0.3 (−3.8, 4.4) |
| No BC | 655 | 4.3 (3.9, 4.8) | −0.4 (−1.0, 0.1) | 0.1 (−0.1, 0.3) | 3.5 (2.8, 4.1) | 4.8 (3.8, 5.9) |
| P-value | 0.212 | 0.954 | 0.735 | 0.293 | 0.036 | |
| Endocrine therapy, no chemotherapy | ||||||
| BC | 264 | 4.3 (3.6, 5.0) | −0.5 (−1.4, 0.4) | 0.1 (−0.2, 0.5) | 3.3 (2.2, 4.4) | 5.7 (4.1, 7.4) |
| No BC | 655 | 4.4 (4.0, 4.9) | −0.6 (−1.1, 0.0) | 0.1 (−0.1, 0.3) | 3.4 (2.8, 4.1) | 4.9 (3.8, 5.9) |
| P-value | 0.791 | 0.926 | 0.993 | 0.836 | 0.396 | |
| Chemotherapy and endocrine therapy | ||||||
| BC | 115 | 3.3 (2.3, 4.3) | −1.2 (−2.6, 0.2) | −0.2 (−0.7, 0.3) | 2.6 (1.0, 4.3) | 3.8 (1.3, 6.3) |
| No BC | 655 | 4.3 (3.9, 4.8) | −0.5 (−1.0, 0.1) | 0.1 (−0.1, 0.4) | 3.5 (2.8, 4.2) | 5.1 (4.1, 6.2) |
| P-value | 0.068 | 0.331 | 0.225 | 0.362 | 0.325 | |
Abbreviations: CVD, cardiovascular disease; BC, breast cancer
a
Adjusted for age at enrollment, time between enrollment and second visit, and enrollment measure