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. 2018 Dec 8;4(12):e01023. doi: 10.1016/j.heliyon.2018.e01023

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© 2018 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 6 — (a) The effect of aprotinin on the NS2B/NS3 protease activity using AlphaScreen^® assay (IC₅₀ value at 0.35 μM) (b) The effects of aprotinin on the NS2B/NS3 protease activity using protease assay (IC₅₀ value at 0.15 μM) (c) The effect of panduratin A on the NS2B/NS3 protease activity using AlphaScreen^® assay (IC₅₀ undetermined) (d) The effect of panduratin A on the NS2B/NS3 protease activity using protease assay (IC₅₀ value at 211.5 μM) (e) The effect of compound 4 on the NS2B/NS3 protease activity using AlphaScreen^® assay (IC₅₀ undetermined) (f) The effect of compound 4 on NS2B/NS3 protease activity using protease assay (IC₅₀ undetermined). Data are presented as mean alphasignal ± SEM of three independent experiments.