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Schematic overview of DNA strand-mediated binding, release, and rebinding of protein-based molecular cargo. Steps: capturing of biotin-tagged anchor strand A-DNA to surface-bound streptavidin (gray) followed by hybridization of conjugate C-DNA and streptavidin; release of protein cargo by toehold-mediated strand displacement with release strand R-DNA; rebinding of C-DNA onto A-DNA.
