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. 2018 Dec 17;4(12):e01055. doi: 10.1016/j.heliyon.2018.e01055

Fig. 1.

Fig. 1

Schematic representation of the main genetic alterations driving the transformation of normal pancreatic tissue in to pancreatic adenocarcinoma, then a list of different phenotypic mechanisms controlling the process of chemoresistance, tumor progression and its metastasis to the liver. L: Liver; S: Stomach; P: Pancreas.