Table 3.
Kruskal–Wallis H Test, Comparison Across 3 Groups; LGG, HGG, and MET and Listed Metabolites
| Kruskal–Wallis Test For–Tissue Type | EDEMA HGG (n = 12), LGG (n = 5), MET (n = 9) | Contrast EnhancementHGG (n = 12), LGG (n = 7), MET (n = 10) | Cyst/Necrosis HGG (n = 9), MET (n = 4) | Ipsilateral NAWM HGG (n = 13), LGG (n = 8), MET (n = 9) | Contralateral NAWM HGG (n = 13), LGG (n = 8), MET (n = 8) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Metabolite Concentration or Ratio with P- and Chi-Square Value | Chi-Square | P-Value < | Chi-Square | P-Value < | Chi-Square | P-Value < | Chi-Square | P-Value < | Chi-Square | P-Value < |
| tLip/tCho | 0.012 | .994 | 12.984 | .002 | 0.857 | .355 | 3.820 | .148 | 0.482 | .786i |
| tLip/tCr | 1.858 | .395 | 4.038 | .133 | 0.024 | .877 | 2.118 | .347 | 1.368 | .505i |
| tMM/tCho | 2.791 | .248 | 2.157 | .340 | 5.357 | .021 | 0.013 | .994 | 1.451 | .484 |
| tMM/tCr | 1.072 | .585a | 0.955 | .620 | 3.429 | .064 | 1.248 | .536 | 0.432 | .806 |
| Ins/tCho | 5.384 | .068b | 13.941 | .001d | 1.444 | .229f | 4.243 | .120 | 1.306 | .520i |
| Ins/tCr | 1.263 | .532b | 1.218 | .544d | 0.419 | .518f | 1.963 | .375 | 2.211 | .331i |
| Ins conc | 2.244 | .326b | 0.862 | .65d | 0.009 | .926f | 2.243 | .326 | 7.005 | .030i |
| Lac/tCho | 4.769 | .092c | 3.645 | .162e | 0.857 | .355 | 1.952 | .377g | 3.262 | .196i |
| Lac/tCr | 4.311 | .116c | 1.087 | .581e | 0.024 | .877 | 2.322 | .313g | 4.924 | .085i |
| Lac conc | 2.807 | .246c | 3.701 | .157e | 0.024 | .877 | 2.058 | .357g | 0.025 | .987 |
| tCho/tCr | 0.265 | .876 | 2.389 | .303 | 0.381 | .537 | 8.204 | .017 | 1.868 | .393 |
| tCho conc | 0.244 | .885 | 0.733 | .693 | 4.024 | .045 | 4.702 | .095 | 0.771 | .680 |
| NAA/tCho | 1.666 | .435 | 0.387 | .824 | 3.429 | .064 | 6.701 | .035h | 1.756 | .416 |
| NAA/tCr | 4.602 | .100 | 0.406 | .816d | 0.214 | .643 | 0.973 | .615 | 0.049 | .976 |
| NAA conc | 0.969 | .616 | 0.066 | .967 | 0.095 | .758 | 1.664 | .435 | 4.928 | .085 |
| tCr/tCho | 6.824 | .033 | 6.439 | .040 | 0.024 | .877 | 1.997 | .368h | 0.890 | .641 |
| tCr conc | 0.566 | .754 | 0.371 | .831 | 0.381 | .537 | 1.495 | .474 | 0.422 | .810 |
| Glx/tCho | 7.421 | .024 | 3.455 | .178 | 1.167 | .280 | 1.310 | .520h | 0.536 | .765 |
| Glx/tCr | 3.904 | .142 | 2.695 | .260 | 1.524 | .217 | 5.237 | .073 | 0.503 | .778 |
| Glx conc | 0.777 | .678 | 1.348 | .510 | 0.857 | .355 | 3.103 | .212 | 0.092 | .955 |
Significance before Bonferroni adjustment set at P-value < .05:
aHGG: n = 11; LGG: n = 5; MET: n = 9;
bHGG: n = 11; LGG: n = 5; MET: n = 8;
cHGG: n = 12; LGG: n = 4; MET: n = 9;
dHGG: n = 12; LGG: n = 7; MET: n = 9;
eHGG: n = 11; LGG: n = 7; MET: n = 9;
fHGG: n = 9; MET: n = 3;
gHGG: n = 12; LGG: n = 8; MET: n = 9;
hHGG: n = 13; LGG: n = 8; MET: n = 8;
iHGG: n = 12; LGG: n = 8; MET: n = 8.