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. 2018 Dec 14;12:2637. doi: 10.2147/OPTH.S196843

A Phase II/III, randomized, double-masked, vehicle-controlled, dose-ranging study of the safety and efficacy of OTX-101 in the treatment of dry eye disease [Corrigendum]

PMCID: PMC6300363  PMID: 30587910

Tauber J, Schechter BA, Bacharach J, et al. Clin Ophthalmol. 2018;12:1921–1929.

On page 1924, Efficacy end points, Conjunctival staining section, the sentence “Statistically significant reductions in the mean change from baseline in the study eye at Day 84 relative to vehicle were observed for both OTX-101 concentrations (P<0.01). The results by study visit are depicted in Figure 3.” should read “Statistically significant reductions in the least squares mean change from baseline in the study eye at Day 84 relative to vehicle were observed for both OTX-101 concentrations (P<0.01). The results by study visit are depicted in Figure 3.”

Figure 3.

Figure 3

The LS mean CFB in total conjunctival lissamine green staining scores by study visit is presented for the vehicle group (open squares), OTX-101 0.05% group (light blue diamonds) and OTX-101 0.09% group (dark blue circles).

Notes: Statistically significant reductions in the LS mean CFB relative to vehicle were observed for OTX-101 0.09% at Day 84 (P=0.0076), and for the OTX-101 0.05% group at Day 56 (P=0.029) and Day 84 (P=0.006).

Abbreviations: CFB, change from baseline; LS, least squares; SE, standard error.

On page 1926, Figure 3 and captions should be replaced as follows:


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