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. 2018 Dec 5;6(4):125. doi: 10.3390/microorganisms6040125

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of time of ciprofloxacin addition at 1 × MIC on the inactivation of bioluminescent E. coli (I) and the phage concentration (II) in TSB during 36 h: (A) antibiotic added after 6 h of phage addition; (B) antibiotic added after 12 h of phage addition; and (C) antibiotic added after 18 h of phage addition. BC, Bacterial control; PC, Phage control; B + P, Bacteria plus phage; B + CipC0h, Bacteria plus antibiotic added at the same time of the phage; B + P + Cip0h, Bacteria plus phage plus antibiotic added at the same time of the phage; B + P + Cip6h, Bacteria plus phage plus antibiotic added at 6 h of phage addition; B + P + Cip12h, Bacteria plus phage plus antibiotic added at 12 h of phage addition; B + P + Cip18h, Bacteria plus phage plus antibiotic added at 18 h of phage addition. Values represent the mean of three independent experiments.