Figure 2.

Examples of phase diagrams showing the formation of curvature-induced domains in planar membranes. Each diagram shows 3 phases: the macrophase separation (M), the modulated phase (or mesophase) (O), and the liquid phase which can be simple (L) or structured disordered (SD) with transient domains. (a) Coupling constant between the two leaflets $m_0$ versus $C_1/C_1^{\ast }$ (see text) from the model by Gueguen et al. in which the two leaflets have the same composition but with different averaged area fractions. SD- (resp. SD+) corresponds to curved (resp. flat) transient domains. Here the bending modulus $\kappa$ does not depend on the phase state. Reproduced from [85], with permission of The European Physical Journal (EPJ), Copyright 2014. (b) Temperature versus $C_1/C_1^{\ast }$ from the model by Shlomovitz and Schick in which each leaflet contains a different mixture of two lipids. (SDin) corresponds to curved transient domains in the inner leaflet only, and (SD) in both leaflets. Adapted from [79], with permission from Elsevier, Copyright 2013.