Table 2.
Composition of hydrogel nanocomposites, murine fibroblast cell viability (%) for iron oxide nanoparticles and hydrogel nanocomposites at 24 h, final temperature values (°C) for the gels exposed to an AMF at 25 kA/m, calculated iron oxide mass for the heated gels (mg/cm3) and AMF strengths (kA/m) needed to achieve hyperthermia and thermo-ablative temperatures [62].
| Macromer Feed | Cross-Linker Feed | Cell Viability | Final Temp. | Fe3O4 Mass/Gel | Hyperthermia AMF Strength | Thermo-ablative AMF Strength |
|---|---|---|---|---|---|---|
| 50 mol % PEG200MMA |
50 mol % PEG400DMA |
95.7 ± 1.4 | 60.7 ± 0.7 | 1.58 | 17.3 | 25.3 |
| 80 mol % PEG200MMA |
20 mol % PEG400DMA |
97.3 ± 0.9 | 59.5 ± 1.1 | 1.92 | 17.4 | 25.9 |
| 95 mol % PEG200MMA |
5 mol % PEG400DMA |
97.9 ± 0.5 | 65.7 ± 1.7 | 2.74 | 16.5 | 24.2 |
| 50 mol % PEG200MMA |
50 mol % TEGDMA |
96.0 ± 2.0 | 66.1 ± 0.7 | 5.32 | 14.7 | 22.0 |
| 50 mol % PEG1000MMA |
50 mol % PEG400DMA |
97.0 ± 2.5 | 73.8 ± 0.8 | 7.24 | 14.3 | 23.0 |
| 50 mol % PEG1000MMA |
50 mol % TEGDMA |
96.9 ± 1.0 | 79.6 ± 1.3 | 7.93 | 12.7 | 17.4 |
| 1000 μg/mL Fe3O4 | 98.0 ± 0.2 | |||||
| Control | 97.9 ± 0.6 |