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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Pain. 2018 Dec;159(12):2512–2521. doi: 10.1097/j.pain.0000000000001355

Figure 5. Morphine administration into the RVM and the rACC (site 2), but not ACC site 1 or 3, elicits CPP in SNL rats.

Figure 5.

(A) Administration of morphine (20 μg/0.5 μl) into the ACC site 1 did not elicit CPP in either SNL (N=16) or sham (N=18) rats. (B) Morphine (10 μg/0.5 μl) into the ACC site 2 produced CPP in SNL (N=10) but not sham (N=8) rats. (C) Morphine (20 μg/0.5 μl) into the ACC site 3 did not produce CPP in SNL (N=18) or sham (N=12) rats. (D) Microinjection of morphine (10 μg/0.5 μl) into the RVM produced CPP in SNL (N=9) but not sham (N=10) rats. *P<0.05, unpaired t-test. Data are means ± SEM.