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. Author manuscript; available in PMC: 2019 Jan 7.
Published in final edited form as: Biochemistry. 2017 Nov 28;56(49):6423–6433. doi: 10.1021/acs.biochem.7b00700

Figure 7.

Figure 7.

Inhibition of EGF-mediated proliferation by rhTIMP-2-6XHis preincubation. MTT assays determed the % max EGF proliferation as described in Materials and Experimental Details (n = 3; mean ± standard error of the mean). Proliferation data were plotted for (A) A549 NSCLC lung cancer cell lines and (B) JygMC(A) triple negative breast cancer cells in gelatin-coated cell culture plates. Proliferation was measured at optimal times following EGF stimulation, 48 and 72 h post-EGF stimulation for A549 and JygMC(A) cells, respectively.