Table 1. Correlation of PARP protein expression with clinico-pathological parameters in breast cancer.

	Total		High expression		Low expression		p value
	N	%	N	%	N	%
Total number of cases	1008		451	44.7	557	55.3
Age Groups
≤ 50	686	68.1	305	44.5	381	55.5	0.7931
>50	322	31.9	146	45.3	176	54.7
Tumor size
T1	219	22.2	82	37.4	137	62.6	0.0136
T2	495	50.3	218	44.0	277	56.0
T3	145	14.7	75	51.7	70	48.3
T4	126	12.8	66	52.4	60	47.6
Lymph Nodes
N0	312	33.0	133	42.6	179	57.4	0.6011
N1	305	32.3	134	43.9	171	56.1
N2	197	20.8	87	44.2	110	55.8
N3	131	13.9	65	49.6	66	50.4
Metastasis
M0	917	91.0	394	43.0	523	57.0	0.0003
M1	91	9.0	57	62.6	34	37.4
Tumour Stage
I	87	9.0	32	36.8	55	63.2	0.0006
II	407	42.1	165	40.5	242	59.5
III	381	39.5	177	46.5	204	53.5
IV	91	9.4	57	62.6	34	37.4
Histological Grade
Well differentiated	81	8.1	21	25.9	60	74.1	<0.0001
Moderately differentiated	511	51.3	205	40.1	306	59.9
Poorly differentiated	405	40.6	224	55.3	181	44.7
Histology
Infiltrating Ductal Carcinoma	917	93.7	421	45.9	496	54.1	0.2681
Infiltrating Lobular	46	4.7	16	34.8	30	65.2
Mucinous Ca	16	1.6	6	37.5	10	62.5
Lymphovascular invasion
Yes	373	41.7	173	46.4	200	53.6	0.6135
No	521	58.3	233	44.7	288	55.3
Triple Negative
No	851	85.1	348	40.9	503	59.1	< 0.0001
Yes	149	14.9	101	67.8	48	32.2
Ki-67 IHC
High	624	63.5	331	53.0	293	47.0	<0.0001
Low	358	36.5	112	31.3	246	68.7
XIAP
High	284	29.5	159	56.0	125	44.0	<0.0001
Low	680	70.5	276	40.6	404	59.4
Survival
OS 5 Years				73.1		85.6	0.0006